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To convert PT-141 — also written PT 141 or bremelanotide — to syringe units, divide your dose in milligrams by the vial’s concentration (mg/mL), then multiply by 100 for a U-100 insulin syringe. Example: a 10 mg vial in 2 mL BAC water is 5 mg/mL, so 1.75 mg (the FDA-labeled amount) draws 35 units. Arithmetic only — not medical advice; verify with a licensed clinician.
PT-141 (Bremelanotide) reconstitution & dosage calculator X
Reconstitution / draw volume / syringe units / supply-chain
Arithmetic checks out. Confirm clinically, against the label, and against the actual vial before any use.
Independent check - dose mg / concentration mg/mL = volume. U-100 units = mL x 100.
1.75 mg at least 45 min before anticipated sexual activity; max 1 dose/24 h and not more than 8/month
Commercial Vyleesi is a 1.75 mg/0.3 mL autoinjector; no reconstitution required.
Contraindicated in uncontrolled hypertension or known cardiovascular disease.
FDA prescribing information (PT-141 (bremelanotide)) - accessdata.fda.govSupply-chain signal only - not a potency guarantee. Enter the COA's tested mg and purity above so the math reflects the real vial.
View on finnrick.comReverse: pick a dose and the units you want it to read, then calculate diluent to add.
Same-syringe co-draw. Reconstitute each peptide in its own vial, then draw them into one syringe.
- Reconstitute each peptide in its own vial — never add water to multiple peptides in one vial.
- Only co-draw peptides with the same diluent (e.g. both bacteriostatic water) and compatible pH.
- Draw and inject fresh — do not pre-mix and store; mixture stability is not established.
- No blended stack is clinically validated. Verify each component and confirm with a clinician.
PT-141 (bremelanotide) dose to syringe units: reference chart
| Vial + water | Concentration | Units per 1 mg | 1.75 mg |
|---|---|---|---|
| 10 mg + 1 mL | 10 mg/mL | 10 | 17.5 |
| 10 mg + 2 mL | 5 mg/mL | 20 | 35 |
| 10 mg + 3 mL | 3.33 mg/mL | 30 | 52.5 |
Concentration = vial strength divided by the bacteriostatic water added. On a U-100 syringe 100 units = 1 mL, so units = (dose divided by concentration) x 100. Values are syringe units, not milligrams. Amber values exceed 100 units, which is more than one standard 1 mL U-100 syringe holds, so that combination needs a more concentrated solution. Columns are the dose steps named on the current FDA label - they describe what has been studied or labeled, not what anyone should take, and this page gives no dosing advice. Multiply the units-per-1-mg figure by your own dose in milligrams to convert any amount. For vial sizes or doses not shown here, use the general mg to units converter.
Sources
- FDA prescribing information (PT-141 (bremelanotide)) - accessdata.fda.govCurrent regulator label. Basis for the regulatory status, route, frequency and published range shown on this page, and for the dose columns in the chart above. Source last checked 2026-06-24
Frequently asked questions
Which condition is the FDA-approved form of bremelanotide indicated for?
Bremelanotide is sold as Vyleesi, approved for acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women (FDA label 210557). That is a narrow, on-demand indication rather than a daily or general-purpose therapy.
Is bremelanotide taken on a fixed weekly schedule like some peptides?
No. Vyleesi is used on demand: one 1.75 mg subcutaneous dose at least 45 minutes before anticipated activity, with the label limiting use to one dose per 24 hours and no more than eight doses per month. This calculator only converts a milligram amount you enter, so it does not plan a schedule.
How does this tool work with a 10 mg research vial of PT-141?
Research-grade PT-141 usually comes as a lyophilized 10 mg vial that you reconstitute before measuring. After you enter the resulting concentration in mg per mL, the calculator converts your target milligram amount into U-100 insulin-syringe units. To decide how much bacteriostatic water to add first, use the /tools/bac-water-calculator.
Do I need to run the branded Vyleesi autoinjector through this calculator?
No. Vyleesi is supplied as a single-use 1.75 mg per 0.3 mL prefilled autoinjector, so there is nothing to mix or convert and it is used exactly as delivered. This tool applies only to loose research vials that you reconstitute yourself.
Does the Vyleesi label flag any cardiovascular cautions for bremelanotide?
Yes. The label lists contraindications for people with uncontrolled hypertension or known cardiovascular disease. This is a factual label note, and whether bremelanotide is appropriate for a given person is a determination for a licensed clinician.