← Full peptide calculator
Free tool
To convert a retatrutide dose to syringe units, divide your dose in milligrams by the vial’s concentration in mg/mL, then multiply by 100. For example, a 10 mg vial reconstituted with 1 mL of bacteriostatic water gives 10 mg/mL, and any 0.05 mL of that solution measures 5 units on a U-100 syringe. This is arithmetic only, not medical advice — verify any dose with a licensed clinician.
Retatrutide reconstitution & dosage calculator X
Reconstitution / draw volume / syringe units / supply-chain
Arithmetic checks out. Confirm clinically, against the label, and against the actual vial before any use.
Independent check - dose mg / concentration mg/mL = volume. U-100 units = mL x 100.
Phase 2 obesity trial tested 1, 4, 8 and 12 mg weekly with study-controlled escalation
Arithmetic only. No approved commercial concentration, label, or self-use titration exists.
Trial doses are not prescribing guidance; formulation and phase-3 protocols may differ.
New England Journal of Medicine - DOI 10.1056/NEJMoa2301972Supply-chain signal only - not a potency guarantee. Enter the COA's tested mg and purity above so the math reflects the real vial.
View on finnrick.comReverse: pick a dose and the units you want it to read, then calculate diluent to add.
Same-syringe co-draw. Reconstitute each peptide in its own vial, then draw them into one syringe.
- Reconstitute each peptide in its own vial — never add water to multiple peptides in one vial.
- Only co-draw peptides with the same diluent (e.g. both bacteriostatic water) and compatible pH.
- Draw and inject fresh — do not pre-mix and store; mixture stability is not established.
- No blended stack is clinically validated. Verify each component and confirm with a clinician.
Retatrutide dose to syringe units: reference chart
| Vial + water | Concentration | Units per 1 mg | 1 mg | 4 mg | 8 mg | 12 mg |
|---|---|---|---|---|---|---|
| 10 mg + 1 mL | 10 mg/mL | 10 | 10 | 40 | 80 | 120 |
| 10 mg + 2 mL | 5 mg/mL | 20 | 20 | 80 | 160 | 240 |
| 10 mg + 3 mL | 3.33 mg/mL | 30 | 30 | 120 | 240 | 360 |
Concentration = vial strength divided by the bacteriostatic water added. On a U-100 syringe 100 units = 1 mL, so units = (dose divided by concentration) x 100. Values are syringe units, not milligrams. Amber values exceed 100 units, which is more than one standard 1 mL U-100 syringe holds, so that combination needs a more concentrated solution. Columns are the doses studied in the published trial - they describe what has been studied or labeled, not what anyone should take, and this page gives no dosing advice. Multiply the units-per-1-mg figure by your own dose in milligrams to convert any amount. For vial sizes or doses not shown here, use the general mg to units converter.
Sources
- New England Journal of Medicine - DOI 10.1056/NEJMoa2301972Published Phase 2 human RCT. Basis for the regulatory status, route, frequency and published range shown on this page, and for the dose columns in the chart above. Source last checked 2026-06-24
Frequently asked questions
What regulatory status does retatrutide have right now?
Retatrutide is an investigational triple agonist (GIP/GLP-1/glucagon) with no marketing approval anywhere. Because nothing has been cleared for sale, there is no approved label, no set concentration, and no sanctioned self-use titration schedule. This tool only converts a mg amount you enter into U-100 syringe units; it does not imply the compound is authorized for personal use.
Which dose amounts appeared in retatrutide’s obesity research, and can I copy them here?
A Phase 2 obesity trial evaluated 1, 4, 8, and 12 mg administered weekly under a study-controlled escalation, so the studied span runs from 1 mg up to 12 mg. Those figures describe a monitored clinical setting only, not a recommended personal regimen. You may type any of them into the calculator purely to see the equivalent U-100 units, but the number itself carries no dosing endorsement.
How does retatrutide’s triple-agonist design change the way I should read this calculator?
Retatrutide acts on three receptors (GIP, GLP-1, and glucagon), whereas most incretin peptides hit one or two. That added glucagon activity is why its research handling differs from single- or dual-agonist compounds. The mechanism does not change the arithmetic here, though: the tool still just divides your mg dose by the mg-per-unit implied by your fill volume. Mechanism questions belong with a clinician, not a units converter.
My retatrutide vial is labeled 10 mg. How does that figure into the math?
A 10 mg vial is the size commonly encountered, but always confirm the actual milligram content against the certificate of analysis (COA) before trusting it, since research-supply labeling can vary. The calculator needs the true vial strength and your reconstitution volume to output U-100 units correctly. If the COA shows a different amount than the label, use the COA number as your input.
Is there a proven PK curve or half-life shown here to help me space retatrutide doses?
No. This site does not publish a pharmacokinetic figure for retatrutide, so the calculator makes no assumptions about half-life, steady state, or dose interval. It performs a single static mg-to-units conversion for the amount you enter and nothing more. Any timing or accumulation decision would require clinical pharmacology data and professional oversight that a units converter cannot supply.